EGFR Antibody
| Code | Size | Price |
|---|
| PSI-79-585-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
ERBB, HER1, mENA, ERBB1, PIG61, Receptor tyrosine-protein kinase ErbB-1
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Background References:
- Noguchi T, et al. (1994) Mol Cell Biol; 14 (10): 6674-6682Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96 (19): 10869-10874Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O?Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
EGFR (Ab-1172) antibody was raised against a peptide sequence around aa. 1170~1174 (P-D-Y-Q-Q) derived from Human EGFR.
NCBI Gene ID #:
1956
NCBI Official Name:
epidermal growth factor receptor
NCBI Official Symbol:
EGFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
175 kDa
Protein Accession #:
NP_005219.2
Protein GI Number:
29725609
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total EGFR protein.
Swissprot #:
P00533