Further Information
GLUH1, GLUR1, GLURA, GluA1, HBGR1, P53, GLR1, GLUH1, GRIA1, GluR-1, GluR-A
Western Blot: 1:500~1:1000
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Emamian ES, et al. (2004) J Neurosci. 24 (7): 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
GluR1 (phospho-Ser836) antibody was raised against a peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1.
Phospho-Specific
2890
glutamate receptor, ionotropic, AMPA 1
GRIA1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
NP_000818.2
167001419
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific,Neuroscience
This antibody detects endogenous level of GluR1 only when phosphorylated at serine 836.
P42261