MEK1 Antibody

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ProSci
Product Code: PSI-79-400
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-400-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HepG2 and PC12 cells using MEK1 (Ab-291).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK1 (Ab-291).
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Western blot analysis of lysed extracts from HepG2 and PC12 cells using MEK1 (Ab-291).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK1 (Ab-291).

Documents

Further Information

Additional Names:
CFC3, MEK1, MKK1, MAPKK1, PRKMK1, MAPTL, MTBT1, TAU, ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
Background References:
  • Kevin D. Burroughs, et, al. (2003) Mol. Cancer Res ; 1: 312. Michael J. Piatelli, et, al. (2002) J. Biol. Chem ; 277: 12144 - 12150. Margaret M. Morgan, et, al. (2001) J. Immunol ; 167: 5708. Herbert Schramek, et, al. (2003) Am J Physiol Cell Physiol, ; 285: C652 - C661.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MEK1 (Ab-291) antibody was raised against a peptide sequence around aa. 289~293 (P-R-T-P-G) derived from Human MEK1.
NCBI Gene ID #:
5604
NCBI Official Name:
mitogen-activated protein kinase kinase 1
NCBI Official Symbol:
MAP2K1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_002746.1
Protein GI Number:
5579478
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total MEK1 protein.
Swissprot #:
Q02750