Neuroserpin Antibody

ProSci
Product Code: PSI-79-721
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-721-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from Mouse brain tissue using Neuroserpin Antibody.

Western blot analysis of extract from Mouse brain tissue using Neuroserpin Antibody.

Further Information

Additional Names:
PI12, neuroserpin, PI12, SERPINI1
Application Note:
Western Blot: 1:500~1:1000
Background:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Background References:
  • Davis R. L., Shrimpton A. E., Holohan P. D., Bradshaw C., Feiglin D., Collins G. H., Sonderegger P., Kinter J., Becker L. M., Lacbawan F., Nature 401:376-379 (1999)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Neuroserpin antibody was raised against a peptide sequence around aa.402~406 (T-S-G-H-D) derived from Human Neuroserpin.
NCBI Gene ID #:
5274
NCBI Official Name:
serpin peptidase inhibitor, clade I (neuroserpin), member 1
NCBI Official Symbol:
SERPINI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
NP_001116224.1
Protein GI Number:
170295807
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience,Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total Neuroserpin protein.
Swissprot #:
Q99574