Oct-1 Antibody
| Code | Size | Price |
|---|
| PSI-79-773-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
OCT1, OTF1, oct-1B, 41183
Application Note:
Western Blot: 1:500~1:1000
Background:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Background References:
- Prefontaine G. G., Walther R., Giffin W., Lemieux M. E., Pope L., Hache R. J. G. J. Biol. Chem, 274:26713-26719 (1999) Mahajan S. S., Wilson A. C. Mol. Cell. Biol. 20:919-928 (2000)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Oct-1 antibody was raised against a peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1.
NCBI Gene ID #:
5451
NCBI Official Name:
POU class 2 homeobox 1
NCBI Official Symbol:
POU2F1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
NP_001185712.1
Protein GI Number:
311771667
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total Oct-1protein.
Swissprot #:
P14859