SEK1/MKK4 Antibody

ProSci
Product Code: PSI-79-331
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-331-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SEK1/MKK4 (Ab-261).
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Immunofluorescence staining of methanol-fixed HeLa cells using SEK1/MKK4 (Ab-261).

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SEK1/MKK4 (Ab-261).
Immunofluorescence staining of methanol-fixed HeLa cells using SEK1/MKK4 (Ab-261).

Further Information

Additional Names:
JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1, C9orf88, JNKK, MAP2K4, MAPK/ERK kinase 4, MAPKK 4
Application Note:
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
Background References:
  • Wang W, et al. (2002) Mol Cell Biol; 22 (10): 3389-403. Leung IW, et al. (2001) J Biol Chem; 276 (3): 1961-7.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SEK1/MKK4 (Ab-261) antibody was raised against a peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.
NCBI Gene ID #:
6416
NCBI Official Name:
mitogen-activated protein kinase kinase 4
NCBI Official Symbol:
MAP2K4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
NP_003001.1
Protein GI Number:
4506889
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total SEK1/MKK4 protein.
Swissprot #:
P45985