SHP-1 Antibody

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ProSci
Product Code: PSI-79-413
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-413-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from 293 cells using SHP-1 (Ab-536).
2 / 2
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-1 (Ab-536).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using SHP-1 (Ab-536).
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Western blot analysis of lysed extracts from 293 cells using SHP-1 (Ab-536).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-1 (Ab-536).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using SHP-1 (Ab-536).

Documents

Further Information

Additional Names:
HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, BLIMP1, 70Z-SHP, EC 3.1.3.48, HCP, Hematopoietic cell protein-tyrosine phosphatase
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
Background References:
  • Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95 (7): 3845-3850. Timms JF, et al. (1998) Mol Cell Biol; 18 (7): 3838-3850. Kanagasundaram V, et al. (1999) Mol Cell Biol; 19 (6): 4079-4092. Hauck CR, et al. (1999) Infect Immun; 67 (10): 5490-5494.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SHP-1 (Ab-536) antibody was raised against a peptide sequence around aa.534~538 (S-E-Y-G-N) derived from Human SHP-1.
NCBI Gene ID #:
5777
NCBI Official Name:
protein tyrosine phosphatase, non-receptor type 6
NCBI Official Symbol:
PTPN6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
NP_002822.2
Protein GI Number:
18104989
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total SHP-1 protein.
Swissprot #:
P29350