Synaptotagmin Antibody
| Code | Size | Price |
|---|
| PSI-79-609-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
P65, SYT, SVP65, SYT1
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse
Background References:
- Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10): 3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18 (5): 1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18 (12): 4957-68.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Synaptotagmin (Ab-309) antibody was raised against a peptide sequence around aa.307~311 (G-L-S-D-P) derived from Human Synaptotagmin.
NCBI Gene ID #:
6857
NCBI Official Name:
synaptotagmin I
NCBI Official Symbol:
SYT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 - 65 kDa
Protein Accession #:
NP_001129277.1
Protein GI Number:
209447070
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous level of total Synaptotagmin protein.
Swissprot #:
P21579