VEGFR2 Antibody

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ProSci
Product Code: PSI-79-313
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-313-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2 (Ab-1175).
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Immunofluorescence staining of methanol-fixed MCF cells using VEGFR2 (Ab-1175).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2 (Ab-1175).
Immunofluorescence staining of methanol-fixed MCF cells using VEGFR2 (Ab-1175).

Documents

Further Information

Additional Names:
FLK1, CD309, VEGFR, VEGFR2, PKD, PKD1, PRKCM, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor
Application Note:
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Background References:
  • Lamalice L, et al. (2004) . Oncogene. 23 (2): 434-445. Takahashi T, et al. (2001) . EMBO J . 20 (11): 2768-2778.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
VEGFR2 (Ab-1175) antibody was raised against a peptide sequence around aa.1173~1177 (K-D-Y-I-V) derived from Human VEGFR2.
NCBI Gene ID #:
3791
NCBI Official Name:
kinase insert domain receptor (a type III receptor tyrosine kinase)
NCBI Official Symbol:
KDR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
230 kDa
Protein Accession #:
NP_002244.1
Protein GI Number:
11321597
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total VEGFR2 protein.
Swissprot #:
P35968