VEGFR2 Antibody
| Code | Size | Price |
|---|
| PSI-79-507-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
FLK1, CD309, VEGFR, VEGFR2, AMPK1, FLK1, KDR
Application Note:
Western Blot: 1:1000
Background:
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Background References:
- Zeng H, et al. (2001) J Biol Chem. 276 (35): 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8): 1619-1627.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
VEGFR2 (phospho-Tyr1059) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1059 (P-D-Y (p) -V-R) derived from Human VEGFR2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3791
NCBI Official Name:
kinase insert domain receptor (a type III receptor tyrosine kinase)
NCBI Official Symbol:
KDR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
230 kDa
Protein Accession #:
NP_002244.1
Protein GI Number:
11321597
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of VEGFR2 only when phosphorylated at Tyrosine 1059.
Swissprot #:
P35968