WASP Antibody

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ProSci
Product Code: PSI-79-733
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-733-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of extract from HeLa, JK and Raji cells using WASP Antibody.
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Western blot analysis of extract from HeLa, JK and Raji cells using WASP Antibody.

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Further Information

Additional Names:
THC, IMD2, SCNX, THC1, WASP, THC
Application Note:
Western Blot: 1:500~1:1000
Background:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
Background References:
  • Kolluri R., Tolias K. F., Carpenter C. L., Rosen F. S., Kirchhausen T. Proc. Natl. Acad. Sci. U. S. A. 93:5615-5618 (1996) Ramesh N., Anton I. M., Hartwig J. H., Geha R. S. Proc. Natl. Acad. Sci. U. S. A. 94:14671-14676 (1997) Cory G. O. C., Cramer R., Blanchoin L., Ridley A. J. Mol. Cell 11:1229-1239 (2003)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
WASP antibody was raised against a peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
NCBI Gene ID #:
7454
NCBI Official Name:
Wiskott-Aldrich syndrome
NCBI Official Symbol:
WAS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
NP_000368.1
Protein GI Number:
4507909
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total WASP protein.
Swissprot #:
P42768