G3BP Antibody
| Code | Size | Price |
|---|
| PSI-XW-7208-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
G3BP antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
G3BP, Ras GTPase-activating protein-binding protein 1, ATP-dependent DNA helicase VIII, G3BP-1, G3BP, HDH-VIII, G3BP(M219)
Application Note:
G3BP(M-219) antibody can be used for the detection of G3BP(M-219) by Western blot, may also work for IHC and ICC.
Background:
Ras-GTPase-activating protein SH3-domain-binding protein; GAP binding protein; RasGAP-associated endoribonuclease G3BP. This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Background References:
- Parker, F., Maurier, F., Delumeau, I., Duchesne, M., Faucher, D., Debussche, L., Dugue, A., Schweighoffer, F., Tocque, B. A Ras-GTPase-activating protein SH3-domain-binding protein. Molec. Cell. Biol. 16: 2561-2569, 1996.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
132-350
NCBI Gene ID #:
10146
NCBI Official Name:
GTPase activating protein (SH3 domain) binding protein 1
NCBI Official Symbol:
G3BP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52.2 kDa (calculated)
Protein Accession #:
NP_005745.1
Protein GI Number:
5031703
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction
Swissprot #:
Q13283
User NOte:
Optimal dilutions for each application to be determined by the researcher.