MAPK1 Antibody

ProSci
Product Code: PSI-XW-7183
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-XW-7183-0.05mg0.05mg£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
MAPK1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot: XW-7183 dilution: 1:2,000. Goat anti-14018-HRP dilution: 1:1,000. E coli-derived fusion protein as test antigen.

Western Blot: XW-7183 dilution: 1:2,000. Goat anti-14018-HRP dilution: 1:1,000. E coli-derived fusion protein as test antigen.

Further Information

Additional Names:
ERK2, PRKM1, PRKM2, Mitogen-activated protein kinase 1, ERT1, MAP kinase 1, ERK, p38, p40, p41, ERK2, ERK-2, MAPK2, P42MAPK, p41mapk, p42-MAPK
Application Note:
ERK2 antibody can be used for the detection of ERK2 by Western blot, may also work for IHC and ICC.
Background:
Mitogen-activated protein kinase 1; extracellular signal-regulated kinase 2; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2. This protein is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Background References:
  • Bhalla, U. S., Ram, P. T., Iyengar, R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023, 2002.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
232-360
NCBI Gene ID #:
5594
NCBI Official Name:
mitogen-activated protein kinase 1
NCBI Official Symbol:
MAPK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41.3 kDa (calculated)
Protein Accession #:
NP_620407.1
Protein GI Number:
20986531
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction, Cancer
Swissprot #:
P28482
User NOte:
Optimal dilutions for each application to be determined by the researcher.