Tryptophan hydroxylase-2 Antibody
| Code | Size | Price |
|---|
| PSI-46-534-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
TPH2, tryptophan hydroxylase 2, HGNC:20692, FLJ37295, NTPH , neuronal tryptophan hydroxylase, ADHD7, MGC138871, MGC138872, tryptophan 5-monooxygenase 2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments in human brain lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).Immunohistochemistry:In paraffin embedded Human Brain Stem shows layered neuronal staining. Recommended concentration: 4-6ug/ml.Immunofluorescence:This product has been successfully used in IF on Mouse: Rahim RS et al, Mol Cell Neurosci.?2018 Apr;88:16-32. PMID: 29187321, and Rahim RS et al, Neuroscience 334 (2016) 201-213.
PMID: 27514574.
Background References:
- Zhou Z, Roy A, Lipsky R, Kuchipudi K, Zhu G, Taubman J, Enoch MA, Virkkunen M, Goldman D. Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations. Arch Gen Psychiatry. 2005 Oct;62(10):1109-18.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-NKPNSGKNDDKGNK
NCBI Gene ID #:
121278
NCBI Official Name:
tryptophan hydroxylase 2
NCBI Official Symbol:
TPH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_775489.2
Protein GI Number:
31795563
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
Q8IWU9