beta-Catenin Antibody

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ProSci
Product Code: PSI-79-201
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-201-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from MCF-7 cells untreated or treated with Calyculin A using β-Catenin (Phospho-Ser33).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using β-Catenin (Phospho-Ser33).
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Western blot analysis of lysed extracts from MCF-7 cells untreated or treated with Calyculin A using β-Catenin (Phospho-Ser33).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using β-Catenin (Phospho-Ser33).

Documents

Further Information

Additional Names:
CTNNB, MRD19, armadillo, EIF4EL1, EIF4F, CTNNB1, CATNB, CTNB1, CTNNB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
Background References:
  • Novak A, et al. (1998) Proc Natl Acad Sci U S A; 95 (8): 4374-4379Marin O, et al. (2003) Proc Natl Acad Sci U S A; 100 (18): 10193-10200Okamura H, et al. (2004) Mol Cell Biol; 24 (10): 4184-4195Xing Y, et al. (2003) Genes Dev; 17 (22): 2753-2764Barth AI, et al. (1999) Proc Natl Acad Sci U S A; 96 (9): 4947-4952
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
beta-Catenin (Phospho-Ser33) antibody was raised against a peptide sequence around phosphorylation site of serine 33 (L-D-S (p) -G-I) derived from Human β-Catenin.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1499
NCBI Official Name:
catenin (cadherin-associated protein), beta 1, 88kDa
NCBI Official Symbol:
CTNNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
NP_001091679.1
Protein GI Number:
148233338
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of β-Catenin only when phosphorylated at serine 33.
Swissprot #:
P35222