Stathmin 1 Antibody

ProSci
Product Code: PSI-79-212
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-212-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Immunohistochemistry (IHC)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 (Phospho-Ser16).

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 (Phospho-Ser16).

Further Information

Additional Names:
Lag, SMN, OP18, PP17, PP19, PR22, LAP18, C1orf215, STK14A, STMN1, STN1, stathmin
Application Note:
I+H157mmunohistochemistry: 1:50~1:100
Background:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.
Background References:
  • Larsson N, et al. (1999) Mol Cell Biol; 19 (3): 2242-2250K?ntziger T, et al. (2001) Mol Biol Cell; 12 (2): 437-448Vadlamudi RK, et al. (2005) Mol Cell Biol; 25 (9): 3726-3736V?zquez-Boland JA, et al. (2001) Clin Microbiol Rev; 14 (3): 584-640Howell B, et al. (1999) Mol Biol Cell; 10 (1): 105-118
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Stathmin 1 (Phospho-Ser16) antibody was raised against a peptide sequence around phosphorylation site of serine 16 (R-A-S (p) -G-Q) derived from Human Stathmin 1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3925
NCBI Official Name:
stathmin 1
NCBI Official Symbol:
STMN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
NP_001138926.1
Protein GI Number:
224451142
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 16.
Swissprot #:
P16949