Stathmin 1 Antibody

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ProSci
Product Code: PSI-79-206
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-206-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from Jurkat cells untreated or treated with PMA using Stathmin 1 (Phospho-Ser25).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 (Phospho-Ser25).
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Western blot analysis of lysed extracts from Jurkat cells untreated or treated with PMA using Stathmin 1 (Phospho-Ser25).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 (Phospho-Ser25).

Documents

Further Information

Additional Names:
Lag, SMN, OP18, PP17, PP19, PR22, LAP18, C1orf215, BIM, STMN1, STN1, stathmin
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
Background References:
  • Boehm M, et al. (2002) EMBO J 21 (13): 3390-3401. Vadlamudi RK, et al. (2005) Mol Cell Biol 25 (9): 3726-3736. Zilfou JT, et al. (2001) Mol Cell Biol 21 (12): 3974-3985. Biernat J, et al. (2002) Mol Biol Cell 13 (11): 4013-4028.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Stathmin 1 (Phospho-Ser25) antibody was raised against a peptide sequence around phosphorylation site of serine 25 (I-L-S (p) -P-R) derived from Human Stathmin 1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3925
NCBI Official Name:
stathmin 1
NCBI Official Symbol:
STMN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
NP_001138926.1
Protein GI Number:
224451142
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 25.
Swissprot #:
P16949