Transthyretin Antibody

ProSci
Product Code: PSI-XW-7686
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-XW-7686-0.05mg0.05mg£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Transthyretin antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temper

Images

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Human plasma protein as test antigen. Affi-pure IgY as primary antibody and Goat-anti-IgY-HRP as 2nd antibody. Fixed amount of Ab (1 ug/mL) and serial dilutions of Ag. E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Human plasma protein as test antigen. Affi-pure IgY as primary antibody and Goat-anti-IgY-HRP as 2nd antibody. Fixed amount of Ab (1 ug/mL) and serial dilutions of Ag. E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Further Information

Additional Names:
PALB, Transthyretin, ATTR, CTS, CTS1, PALB, TBPA, HEL111, HsT2651, TTR, Prealbumin
Application Note:
Transthyretin antibody can be used for the detection of Transthyretin by ELISA and Western Blot, may also work for ICC and IHC.
Background:
FUNCTION: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

DISEASE: Defects in TTR are a cause of hyperthyroxinemia [MIM:176300].

SUBUNIT: Homotetramer.

SIMILARITY: Belongs to the transthyretin family.

SUBCELLULAR LOCATION: Secreted protein.

TISSUE SPECIFICITY: Most abundant in the choroid plexus. Also present in the liver.

DOMAIN: Each monomer has two 4-stranded β sheets and the shape of a prolate ellipsoid. Antiparallel β-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex β-sheets of the dimers to form an internal channel.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
1-147
NCBI Gene ID #:
7276
NCBI Official Name:
transthyretin
NCBI Official Symbol:
TTR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15.9 kDa (calculated)
Protein Accession #:
P02766
Protein GI Number:
136464
Purification:
Immunoaffinity Purified
Swissprot #:
P02766
User NOte:
Optimal dilutions for each application to be determined by the researcher.