RELA Antibody
| Code | Size | Price |
|---|
| PSI-31-180-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RELA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RELA, p65, NFKB3
Application Note:
RELA antibody can be used for detection of RELA by ELISA at 1:62500. RELA antibody can be used for detection of RELA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
p65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
Background References:
- Ruben, S.M., et al., (1991) Science 251 (5000) 1490-1493..
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RELA.
NCBI Gene ID #:
5970
NCBI Official Name:
v-rel avian reticuloendotheliosis viral oncogene homolog A
NCBI Official Symbol:
RELA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_068810
Protein GI Number:
223468676
Purification:
Antibody is purified by Protein A/G affinity chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction ,Immunology ,Apoptosis ,
Swissprot #:
Q04206
User NOte:
Optimal dilutions for each application to be determined by the researcher.