TLE2 Antibody
| Code | Size | Price |
|---|
| PSI-25-059-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TLE2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TLE2, ESG, ESG2, FLJ41188, GRG2
Application Note:
TLE2 antibody can be used for detection of TLE2 by ELISA at 1:312500. TLE2 antibody can be used for detection of TLE2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Background References:
- Higa, L.A., (2006) Nat. Cell Biol. 8 (11), 1277-1283.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TLE2.
NCBI Gene ID #:
7089
NCBI Official Name:
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
NCBI Official Symbol:
TLE2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
NP_003251
Protein GI Number:
21361151
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Signal Transduction
Swissprot #:
Q04725
User NOte:
Optimal dilutions for each application to be determined by the researcher.