CSHL1 Antibody

ProSci
Product Code: PSI-25-733
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-733-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CSHL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Placenta at 0.2-1 ug/ml.

Antibody used in WB on Human Placenta at 0.2-1 ug/ml.

Further Information

Additional Names:
CSHL1, CS-5, CSHP1, CSL, MGC149868, hCS-L
Application Note:
CSHL1 antibody can be used for detection of CSHL1 by ELISA at 1:62500. CSHL1 antibody can be used for detection of CSHL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Sigal, E., (1994) J. Biol. Chem. 269 (37), 23220-23229.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSHL1.
NCBI Gene ID #:
1444
NCBI Official Name:
chorionic somatomammotropin hormone-like 1
NCBI Official Symbol:
CSHL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
NP_072103
Protein GI Number:
12545381
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Signal Transduction ,Growth Factor
Swissprot #:
Q14406
User NOte:
Optimal dilutions for each application to be determined by the researcher.