DUSP6 Antibody

ProSci
Product Code: PSI-XW-7838
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-XW-7838-0.05mg0.05mg£801.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
DUSP6 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:1000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:1000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Further Information

Additional Names:
MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, HH19, MKP3, Dual specificity phosphatase 6
Application Note:
Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.
Background:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
135-280
NCBI Gene ID #:
1848
NCBI Official Name:
dual specificity phosphatase 6
NCBI Official Symbol:
DUSP6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15.1 kDa (calculated)
Protein Accession #:
NP_001937.1
Protein GI Number:
4503419
Purification:
Immunoaffinity Purified
Research Area:
Signal Transduction
Swissprot #:
Q16828
User NOte:
Optimal dilutions for each application to be determined by the researcher.