AFP Antibody
| Code | Size | Price |
|---|
| PSI-XW-7017-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
AFP antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, FETA, HPAFP,
Application Note:
AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.
Background:
α-1-fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Background References:
- Gabant, P., Forrester, L., Nichols, J., Van Reeth, T., De Mees, C., Pajack, B., Watt, A., Smitz, J., Alexandre, H., Szpirer, C., Szpirer, J. Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc. Nat. Acad. Sci. 99: 12865-12870, 2002.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
180-420
NCBI Gene ID #:
174
NCBI Official Name:
alpha-fetoprotein
NCBI Official Symbol:
AFP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68.7 kDa (calculated)
Protein Accession #:
NP_001125.1
Protein GI Number:
4501989
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction, Stem Cell
Swissprot #:
P02771
User NOte:
Optimal dilutions for each application to be determined by the researcher.