Activin receptor-like kinase 1 Antibody

ProSci
Product Code: PSI-45-200
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-200-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-200 (2ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

45-200 (2ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, activin A receptor type II-like 1, Activin A receptor, type II-like kinase 1, ALK1, TSR-I, TGF-B superfamily receptor type I, activin A receptor, type II-like kinase 1, serine/threonine-protein kinase receptor R3
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 60kDa band observed in lysates of cell line MCF7 (calculated MW of 56.1kDa according to NP_000011.2). Recommended concentration: 1-3ug/ml.
Background References:
  • Johnson DW, Berg JN, Baldwin MA, Gallione CJ, Marondel I, Yoon SJ, Stenzel TT, Speer M, Pericak-Vance MA, Diamond A, Guttmacher AE, Jackson CE, Attisano L, Kucherlapati R, Porteous ME, Marchuk DA. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet. 1996 Jun;13(2):189-95.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-KISNSPEKPKVIQ
NCBI Gene ID #:
94
NCBI Official Name:
activin A receptor type II-like 1
NCBI Official Symbol:
ACVRL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000011.2, NP_001070869.1
Protein GI Number:
116734712
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
Please note that this product is not to be confused with the similarly named ALK (anaplastic lymphoma kinase, GeneID 238). Reported variant represent identical protein: NP_000011.2; NP_001070869.1
Swissprot #:
P37023