TFEB Antibody
| Code | Size | Price |
|---|
| PSI-28-949-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TFEB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TFEB, TCFEB, BHLHE35, ALPHATFEB
Application Note:
TFEB antibody can be used for detection of TFEB by ELISA at 1:312500. TFEB antibody can be used for detection of TFEB by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21;q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Background References:
- Argani, P., et al., (2005) Am. J. Surg. Pathol. 29 (2), 230-240.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFEB.
NCBI Gene ID #:
7942
NCBI Official Name:
transcription factor EB
NCBI Official Symbol:
TFEB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
NP_009093
Protein GI Number:
24307933
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
P19484
User NOte:
Optimal dilutions for each application to be determined by the researcher.