WDR39 Antibody
| Code | Size | Price |
|---|
| PSI-28-080-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store WDR39 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
WDR39, CIAO1, CIA1, WDR39
Application Note:
WDR39 antibody can be used for detection of WDR39 by ELISA at 1:62500. WDR39 antibody can be used for detection of WDR39 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Background References:
- Johnstone, R.W., (1998) J. Biol. Chem. 273 (18), 10880-10887.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR39.
NCBI Gene ID #:
9391
NCBI Official Name:
cytosolic iron-sulfur assembly component 1
NCBI Official Symbol:
CIAO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
NP_004795
Protein GI Number:
4757988
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
O76071
User NOte:
Optimal dilutions for each application to be determined by the researcher.