GABRB2 Antibody
| Code | Size | Price |
|---|
| PSI-42-064-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
GABRB2, gamma-aminobutyric acid (GABA) A receptor, beta 2, MGC119386, MGC119388, MGC119389, OTTHUMP00000160872
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Preliminary experiments gave an approx 80kDa band in Mouse Brain lysates after 0.2 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 59.2kDa according to Human NP_068711.1 and 54.6kDa according to Mouse NP_032096.1. The 80kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
- Lo WS, Lau CF, Xuan Z, Chan CF, Feng GY, He L, Cao ZC, Liu H, Luan QM, Xue H. Association of SNPs and haplotypes in GABAA receptor beta2 gene with schizophrenia. Mol. Psychiatry 2004 Jun 9 (6): 603-8.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-HSFGRNALERHVAQ
NCBI Gene ID #:
2561
NCBI Official Name:
gamma-aminobutyric acid (GABA) A receptor, beta 2
NCBI Official Symbol:
GABRB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_068711.1, NP_000804.1
Protein GI Number:
12548785
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_068711.1; NP_000804.1).
Swissprot #:
P47870