MCL1 Antibody

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ProSci
Product Code: PSI-45-872
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-872-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-872 staining (1ug/ml) of Human Lung lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
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45-872 staining (1ug/ml) of Human Lung lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

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Further Information

Additional Names:
MCL1, TM, EAT, MCL1L, MCL1S, MGC1839, MGC104264, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia sequence 1, myeloid cell leukemia sequence 1, isoform 1, BCL2L3, Mcl-1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Approx 35kDa band observed in lysates of Human Lung (calculated MW of 37.3kDa according to NP_068779.1). Recommended concentration: 1-3ug/ml.
Background References:
  • Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature. 2003 Dec 11;426(6967):671-6.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-AGVGAGLAYLIR
NCBI Gene ID #:
4170
NCBI Official Name:
myeloid cell leukemia sequence 1 (BCL2-related)
NCBI Official Symbol:
MCL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_068779.1, NP_001184249.1
Protein GI Number:
11386165
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise reported isoform 1 (NP_068779.1) and isoform 3 (NP_001184249.1).
Swissprot #:
Q07820