IL-1a Monoclonal Antibody

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ProSci
Product Code: PSI-32-178
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-178-0.1mg0.1mg£452.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 1F3B3
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
IL-1a monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using IL - 1a monoclonal antibody against truncated IL - 1a recombinant protein.
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Western blot analysis using IL - 1a monoclonal antibody against truncated IL - 1a recombinant protein.

Documents

Further Information

Additional Names:
IL1F1, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA
Application Note:
Western Blot:1:500 - 1,000
ELISA:Determining optimal working dilutions by titration test.
Background:
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Background References:
  • Du,Y.; et al. 2000. Neurology 55: 480-484.
  • Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified recombinant human IL-1α expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3552
NCBI Official Name:
interleukin 1, alpha
NCBI Official Symbol:
IL1A
NCBI Organism:
Homo sapiens
Protein Accession #:
P01583
Protein GI Number:
124297
Research Area:
Immunology ,Innate Immunity ,Neuroscience
Swissprot #:
P01583
User NOte:
Optimal dilutions for each application to be determined by the researcher.