CKit Monoclonal Antibody

Contact us
ProSci
Product Code: PSI-32-138
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-138-0.1mL0.1mL£560.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 8D7B4
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
C-Kit monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis using C - kit monoclonal antibody against truncated C - kit recombinant protein
2 / 2
❮❯

Western blot analysis using C - kit monoclonal antibody against truncated C - kit recombinant protein

Documents

Further Information

Additional Names:
SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117
Application Note:
Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
Background:
C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Background References:
  • Mojica WD et.alHistopathology. 2005 Nov;47(5):517-22.
  • Tong WD et.alInt J Colorectal Dis. 2005 Jul;20(4):363-7. Epub 2005 Feb 2.
  • Nakai Y et.alBiochem Biophys Res Commun. 2005 Nov 11;337(1):289-96.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3815
NCBI Official Name:
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Official Symbol:
KIT
NCBI Organism:
Homo sapiens
Protein Accession #:
P10721
Protein GI Number:
125472
Purification:
Antibody is purified by protein A affinity chromatography.
Research Area:
Innate Immunity
Swissprot #:
P10721
User NOte:
Optimal dilutions for each application to be determined by the researcher.