LSD1 AOF2 Monoclonal Antibody

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ProSci
Product Code: PSI-32-188
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-188-0.1mg0.1mg£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 1B2F2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
LSD1/AOF2 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using LSD1 monoclonal antibody against truncated LSD1 recombinant protein Hela cell lysate. and Jurkat cell lysate .
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Western blot analysis using LSD1 monoclonal antibody against truncated LSD1 recombinant protein Hela cell lysate. and Jurkat cell lysate .

Documents

Further Information

Additional Names:
AOF2, KDM1, KIAA0601, LSD1, BRAF35-HDAC complex protein BHC110AOF2, BHC110
Application Note:
Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
The amine oxidase domain 2?AOF2?gene encodes a nuclear protein(LSD1,~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Background References:
  • Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64.
  • Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
23028
NCBI Official Name:
lysine (K)-specific demethylase 1A
NCBI Official Symbol:
KDM1A
NCBI Organism:
Homo sapiens
Protein Accession #:
O60341
Protein GI Number:
51315808
Swissprot #:
O60341
User NOte:
Optimal dilutions for each application to be determined by the researcher.