NCOR1 Antibody

ProSci
Product Code: PSI-27-612
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-612-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NCOR1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Intestine.
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Antibody used in IHC on Human Intestine.

Further Information

Additional Names:
NCOR1, N-CoR, TRAC1, N-CoR1, hN-CoR
Application Note:
NCOR1 antibody can be used for detection of NCOR1 by ELISA at 1:62500. NCOR1 antibody can be used for detection of NCOR1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Background References:
  • Horlein, A.J., et al., (1995) Nature 377 (6548), 397-404.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCOR1.
NCBI Gene ID #:
9611
NCBI Official Name:
nuclear receptor corepressor 1
NCBI Official Symbol:
NCOR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
Protein Accession #:
Q86YY0
Protein GI Number:
74759545
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q86YY0
User NOte:
Optimal dilutions for each application to be determined by the researcher.