OLIG2 Antibody

ProSci
Product Code: PSI-27-353
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-353-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store OLIG2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on human LCL and mouse brains at 1:1000.
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Antibody used in IHC on human LCL and mouse brains at 1:500.

Antibody used in WB on human LCL and mouse brains at 1:1000.
Antibody used in IHC on human LCL and mouse brains at 1:500.

Further Information

Additional Names:
OLIG2, BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Application Note:
OLIG2 antibody can be used for detection of OLIG2 by ELISA at 1:62500. OLIG2 antibody can be used for detection of OLIG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t (14;21) (q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14;21) (q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Mitkus, S.N., Schizophr. Res. 98 (1-3), 129-138 (2008).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OLIG2.
NCBI Gene ID #:
10215
NCBI Official Name:
oligodendrocyte lineage transcription factor 2
NCBI Official Symbol:
OLIG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_005797
Protein GI Number:
17978475
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q13516
User NOte:
Optimal dilutions for each application to be determined by the researcher.