ONECUT1 Antibody

ProSci
Product Code: PSI-25-436
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-436-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ONECUT1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Brain, cerebellum at 5.0 ug/ml.
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Antibody used in IHC on Human Brain, cerebellum at 5.0 ug/ml.

Further Information

Additional Names:
ONECUT1, HNF-6, HNF6, HNF6A
Application Note:
ONECUT1 antibody can be used for detection of ONECUT1 by ELISA at 1:312500. ONECUT1 antibody can be used for detection of ONECUT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Background References:
  • Jiang, X., (2008) Oncol. Rep. 19 (1), 157-163.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ONECUT1.
NCBI Gene ID #:
3175
NCBI Official Name:
one cut homeobox 1
NCBI Official Symbol:
ONECUT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
NP_004489
Protein GI Number:
24307887
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q9UBC0
User NOte:
Optimal dilutions for each application to be determined by the researcher.