RUNX1 Antibody

Contact us
ProSci
Product Code: PSI-28-784
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-784-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RUNX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

1 / 1
Antibody used in WB on Human Jurkat cells at 0.2-1 ug/ml.
❮❯

Antibody used in WB on Human Jurkat cells at 0.2-1 ug/ml.

Documents

Further Information

Additional Names:
RUNX1, AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1
Application Note:
RUNX1 antibody can be used for detection of RUNX1 by ELISA at 1:12500. RUNX1 antibody can be used for detection of RUNX1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia.
Background References:
  • Ghozi, M.C., et al., (1996) Proc. Natl. Acad. Sci. U.S.A. 93 (5), 1935-1940.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUNX1.
NCBI Gene ID #:
861
NCBI Official Name:
runt-related transcription factor 1
NCBI Official Symbol:
RUNX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
12 kDa
Protein Accession #:
AAC05247
Protein GI Number:
2944214
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q01196
User NOte:
Optimal dilutions for each application to be determined by the researcher.