IL-6 Monoclonal Antibody

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ProSci
Product Code: PSI-32-179
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-179-0.1mg0.1mg£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 6D9A1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
IL-6 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis using IL6 monoclonal antibody against truncated IL6 recombinant protein.
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Western blot analysis using IL6 monoclonal antibody against truncated IL6 recombinant protein.

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Further Information

Additional Names:
HGF, HSF, BSF2, IL-6, IFNB2
Application Note:
Western Blot:1:200 - 1:1,000
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
Background:
Interleukine 6 (IL-6) is a cytokine produced primarily by stimulated monocytes, fibroblasts and epithelial cells. It has a wide variety of biological functions through activating a cellsurface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. The cytokine plays an essential role in the final differentiation of b-cells into Igsecreting cells, and induces myeloma, plasmacytoma growth, nerve cells differentiations. In addition, IL-6 is an important regulator of acute phase reaction.
Background References:
  • Ota, N. et al. 2001. J. Hum. Genet. 46: 267-272.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified recombinant human IL-6 expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3569
NCBI Official Name:
interleukin 6 (interferon, beta 2)
NCBI Official Symbol:
IL6
NCBI Organism:
Homo sapiens
Protein Accession #:
NP_000591.1
Protein GI Number:
10834984
Research Area:
Immunology ,Immunology , Neuroscience
Swissprot #:
P05231
User NOte:
Optimal dilutions for each application to be determined by the researcher.