EphA1 Monoclonal Antibody
| Code | Size | Price |
|---|
| PSI-32-150-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 5D2A4
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
EphA1 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
EPH, EPHT, EPHT1
Application Note:
Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
Background References:
- Shannon L. Duffy, Kirsten A. Steiner, Patrick P.L. Tam Gene Expr Patterns. 2006 Feb 6.
- Elena B. Pasquale. Nat Rev Mol Cell Biol.2005 Jun; 6(6): 462-75.
Buffer:
Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
2041
NCBI Official Name:
EPH receptor A1
NCBI Official Symbol:
EPHA1
NCBI Organism:
Homo sapiens
Protein Accession #:
NP_005223.4
Protein GI Number:
221316650
Purification:
Antibody is purified by protein A affinity chromatography.
Research Area:
Neuroscience ,Growth Factor
Swissprot #:
P21709
User NOte:
Optimal dilutions for each application to be determined by the researcher.