GSTP1 Monoclonal Antibody

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ProSci
Product Code: PSI-32-167
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-167-0.1mg0.1mg£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3F2C2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
GSTP1 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using GSTP1 monoclonal antibody against full - length GSTP1 recombinant protein.
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Western blot analysis using GSTP1 monoclonal antibody against full - length GSTP1 recombinant protein.

Documents

Further Information

Additional Names:
FAEES3, GST3, GST class-piPI, DFN7, GSTP, FAEES3, HEL-S-22
Application Note:
Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
Background References:
  • Kimihiko Satoh, Ken Itoh, Masayuki Yamamoto. 2002. Carcinogenesis. 23: 457 - 462.
  • Kimihiko Satoh, Ken Itoh, Masayuki Yamamoto. 2002. Carcinogenesis. 23: 457 - 462.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
2950
NCBI Official Name:
glutathione S-transferase pi 1
NCBI Official Symbol:
GSTP1
NCBI Organism:
Homo sapiens
Protein Accession #:
P09211
Protein GI Number:
121746
Research Area:
Growth Factor ,Neuroscience
Swissprot #:
P09211
User NOte:
Optimal dilutions for each application to be determined by the researcher.