Survivin Monoclonal Antibody
| Code | Size | Price |
|---|
| PSI-32-222-0.1mL | 0.1mL | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 2H5H2
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Survivin monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
API4, IAP4, Apoptosis inhibitor 4API4, EPR-1
Application Note:
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
Baculoviral IAP repeat-containing 5 (survivin).This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Background References:
- Urology. 2007 Sep;70(3):482-6.
- World J Gastroenterol. 2007 May 28;13(20):2784-90.
- Histopathology. 2007 Jun;50(7):835-42.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified full-length recombinant Survivin-His is expressed in E.Coli strain BL21 (DE3).The antigen is soluble.
NCBI Gene ID #:
332
NCBI Official Name:
baculoviral IAP repeat containing 5
NCBI Official Symbol:
BIRC5
NCBI Organism:
Homo sapiens
Protein Accession #:
O15392
Protein GI Number:
380865472
Research Area:
Apoptosis ,Growth Factor ,Neuroscience ,Cancer
Swissprot #:
O15392
User NOte:
Optimal dilutions for each application to be determined by the researcher.