MAPK11 Monoclonal Antibody
| Code | Size | Price |
|---|
| PSI-32-190-0.1mL | 0.1mL | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 4H6H6
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
MAPK11 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2
Application Note:
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Background References:
- Mol Cell Biol. 2005 Dec;25(23):10454-64.
- Biol Reprod. 2005 Dec;73(6):1282-8. Epub 2005 Aug 24.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified truncated recombinant MAPK11 (aa251-363)-Trx fusion protein is expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
5600
NCBI Official Name:
mitogen-activated protein kinase 11
NCBI Official Symbol:
MAPK11
NCBI Organism:
Homo sapiens
Protein Accession #:
NP_002742.3
Protein GI Number:
20128774
Research Area:
Signal Transduction
Swissprot #:
Q15759
User NOte:
Optimal dilutions for each application to be determined by the researcher.