FOXO3 Antibody

ProSci
Product Code: PSI-28-775
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-775-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FOXO3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

1 / 5
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.
2 / 5
3 / 5
Antibody used in WB on Hum. Fetal Lung at 1 ug/ml.
4 / 5
Antibody used in WB on Hum. Fetal Liver at 1 ug/ml.
5 / 5
Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.

Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.
Antibody used in WB on Hum. Fetal Lung at 1 ug/ml.
Antibody used in WB on Hum. Fetal Liver at 1 ug/ml.
Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.

Further Information

Additional Names:
FOXO3, AF6q21, DKFZp781A0677, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, MGC12739, MGC31925
Application Note:
FOXO3 antibody can be used for detection of FOXO3 by ELISA at 1:312500. FOXO3 antibody can be used for detection of FOXO3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Background References:
  • Pew, T., (2008) Endocrinology 149 (5), 2637-2645.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXO3.
NCBI Gene ID #:
2309
NCBI Official Name:
forkhead box O3
NCBI Official Symbol:
FOXO3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
NP_001446
Protein GI Number:
4503739
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer ,Apoptosis
Swissprot #:
O43524
User NOte:
Optimal dilutions for each application to be determined by the researcher.