ESRRG Antibody

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ProSci
Product Code: PSI-27-388
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-27-388-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Fish
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ESRRG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Lung lysate.
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Antibody used in WB on Jurkat 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).
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Antibody used in IHC on Human Lung lysate.
Antibody used in WB on Jurkat 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).

Documents

Further Information

Additional Names:
ESRRG, ERR3, NR3B3, ERRgamma
Application Note:
ESRRG antibody can be used for detection of ESRRG by ELISA at 1:62500. ESRRG antibody can be used for detection of ESRRG by western blot at 0.5&micr μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.
Background References:
  • Hentschke, M., et al., (2003) Biochem. Biophys. Res. Commun. 312 (4), 975-982.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ESRRG.
NCBI Gene ID #:
2104
NCBI Official Name:
estrogen-related receptor gamma
NCBI Official Symbol:
ESRRG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
NP_996318
Protein GI Number:
45545429
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction
Swissprot #:
O75454
User NOte:
Optimal dilutions for each application to be determined by the researcher.