NFKBIB Antibody
| Code | Size | Price |
|---|
| PSI-28-111-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NFKBIB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
NFKBIB, IKBB, TRIP9
Application Note:
NFKBIB antibody can be used for detection of NFKBIB by ELISA at 1:62500. NFKBIB antibody can be used for detection of NFKBIB by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.
Background References:
- Lee, Y., et al., (2003) Mol. Hum. Reprod. 9 (4), 213-218.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFKBIB.
NCBI Gene ID #:
4793
NCBI Official Name:
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NCBI Official Symbol:
NFKBIB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
NP_002494
Protein GI Number:
21361135
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction
Swissprot #:
Q15653
User NOte:
Optimal dilutions for each application to be determined by the researcher.