TUG Monoclonal Antibody
Code | Size | Price |
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PSI-32-195-0.1mL | 0.1mL | £524.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 4A11A6G11
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Mouse TUG monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
ASPL, RCC17, TUG, UBXD9, UBXN9, Alveolar soft part sarcoma chromosomal region candidate gene 1 proteinTUG, ASPL, ASPS, ASPCR1
Application Note:
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Background References:
- Nature 2003,425:727 - 733.
Buffer:
Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
79058
NCBI Official Name:
alveolar soft part sarcoma chromosome region, candidate 1
NCBI Official Symbol:
ASPSCR1
NCBI Organism:
Homo sapiens
Protein Accession #:
Q9BZE9
Protein GI Number:
74717746
Purification:
Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.
Research Area:
Growth Factor
Swissprot #:
Q9BZE9
User NOte:
Optimal dilutions for each application to be determined by the researcher.