TIRAP Antibody

ProSci
Product Code: PSI-46-500
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-500-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-500 (1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

46-500 (1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
TIRAP, Mal, toll-interleukin 1 receptor (TIR) domain-containing adapter protein, adapter protein wyatt, MyD88 adapter-like protein, FLJ42305, wyatt, OTTHUMP00000179130, Toll-interleukin 1 receptor domain-containing adaptor protein, Toll-like receptor adaptor protein, adapter protein wyatt
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 30kDa band observed in Human Liver lysates (calculated MW of 25.3kDa according to NP_683708.1). Recommended concentration: 1-3ug/ml.
Background References:
  • Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Blood. 2004 Mar 15;103(6):2229-37.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-EGEGERDSATVSDL
NCBI Gene ID #:
114609
NCBI Official Name:
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
NCBI Official Symbol:
TIRAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_683708.1
Protein GI Number:
22547219
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer ,Infectious Disease
SPECIFICITY:
This protein is expected to recognise isoform b (NP_683708.1) only.
Swissprot #:
P58753