ANP32A Antibody
| Code | Size | Price |
|---|
| PSI-29-209-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ANP32A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
ANP32A, LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Application Note:
ANP32A antibody can be used for detection of ANP32A by ELISA at 1:312500. ANP32A antibody can be used for detection of ANP32A by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Background References:
- Stelzl, U., (2005) Cell 122 (6), 957-968.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANP32A.
NCBI Gene ID #:
8125
NCBI Official Name:
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
NCBI Official Symbol:
ANP32A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
NP_006296
Protein GI Number:
5453880
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction ,Immunology
Swissprot #:
P39687
User NOte:
Optimal dilutions for each application to be determined by the researcher.