EGLN2 Antibody
| Code | Size | Price |
|---|
| PSI-28-104-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store EGLN2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
EGLN2, EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
Application Note:
EGLN2 antibody can be used for detection of EGLN2 by ELISA at 1:1562500. EGLN2 antibody can be used for detection of EGLN2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
Background References:
- Appelhoff, R.J., et al., (2004) J. Biol. Chem. 279 (37), 38458-38465.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EGLN2.
NCBI Gene ID #:
112398
NCBI Official Name:
egl-9 family hypoxia-inducible factor 2
NCBI Official Symbol:
EGLN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
NP_444274
Protein GI Number:
16604260
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction ,Immunology
Swissprot #:
Q96KS0
User NOte:
Optimal dilutions for each application to be determined by the researcher.