S100B Monoclonal Antibody

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ProSci
Product Code: PSI-32-214
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-214-0.1mL0.1mL£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 9A11B9
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
S100B monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using anti - S100B monoclonal antiobdy against full - length S100B recombinant protein.
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Western blot analysis using anti - S100B monoclonal antiobdy against full - length S100B recombinant protein.

Documents

Further Information

Additional Names:
S-100 protein beta chainNEF, S100, S100-B, S100beta
Application Note:
Western Blot:1:500 - 1:2,000 b<>IHC(P):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Background References:
  • Shapiro LA. Marks A. Whitaker-Azmitia PM. Brain Res. 2004, Jun 4,1010(1-2):17-21.
  • Sorci G. Riuzzi F. Arcuri C. et al. Mol Cell Biol. 2004, Jun,24(11):4880-94.
  • Zimmer DB. Chaplin J. Baldwin A. et al. Cell Mol Biol (Noisy-le-grand).2005,Sep 5,51(2):201-14.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified full-length recombinant S100B-GST expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
6285
NCBI Official Name:
S100 calcium binding protein B
NCBI Official Symbol:
S100B
NCBI Organism:
Homo sapiens
Protein Accession #:
P04271
Protein GI Number:
134138
Research Area:
Neuroscience
Swissprot #:
P04271
User NOte:
Optimal dilutions for each application to be determined by the researcher.