DEAF1 Antibody
| Code | Size | Price |
|---|
| PSI-25-520-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DEAF1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
DEAF1, NUDR, SPN, ZMYND5
Application Note:
DEAF1 antibody can be used for detection of DEAF1 by ELISA at 1:12500. DEAF1 antibody can be used for detection of DEAF1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Background References:
- Czesak, M., (2006) J. Neurosci. 26 (6), 1864-1871.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEAF1.
NCBI Gene ID #:
10522
NCBI Official Name:
DEAF1 transcription factor
NCBI Official Symbol:
DEAF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
NP_066288
Protein GI Number:
38016945
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Membrane
Swissprot #:
O75398
User NOte:
Optimal dilutions for each application to be determined by the researcher.