SF1 Antibody
| Code | Size | Price |
|---|
| PSI-29-534-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SF1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
SF1, D11S636, ZFM1, ZNF162, BBP, MBBP, ZCCHC25
Application Note:
SF1 antibody can be used for detection of SF1 by ELISA at 1:12500. SF1 antibody can be used for detection of SF1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Background References:
- Rino, J., (2008) Mol. Cell. Biol. 28 (9), 3045-3057.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SF1.
NCBI Gene ID #:
7536
NCBI Official Name:
splicing factor 1
NCBI Official Symbol:
SF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
NP_973724
Protein GI Number:
42544125
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,RNA Binding
Swissprot #:
Q15637
User NOte:
Optimal dilutions for each application to be determined by the researcher.